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Yes, and this is one of its key advantages
Many people who successfully lost weight on Ozempic and other GLP-1 agonist drugs are having trouble weaning themselves off the injectables, according to the BBC , because the hunger for food comes roaring back with a vengeance and hence the pounds start creeping up again, hinting that patients are likely to develop life-long dependencies on the substances
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GLP-1 receptors throughout the intestinal tract modulate peristalsis, which can result in either constipation or diarrhea
doi: 10.1002/hsr2.2004
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